Ian Roundtree is a highly skilled Resident Physician at Massachusetts General Hospital specializing in the intersection of research and medicine. His background displays a dedication to scientific exploration, as evidenced by his training in synthetic organic chemistry and its applications to biological systems. His undergraduate research centered on the synthesis of biologically active small molecules, while his graduate focus was on genetic regulation through mRNA methylation. He is deeply interested in challenging fundamental beliefs about biology and disease in an effort to identify unique biological principles that can be harnessed for therapeutic applications.
Roundtree, who began his medical career in Boston, has an impressive academic background with degrees from Boston College and the University of Chicago. As a PhD candidate, he spent eight years as a MD/PhD Trainee at the University of Chicago, during which time he also served as a Research Associate in Chemistry at Boston College. During his tenure at Boston College, he developed synthetic methods in organic chemistry and applied them to the construction of carbon-carbon bonds from inexpensive starting materials. Roundtree possesses a strong suite of skills including molecular biology and RNA sequencing, which he has honed throughout his education and career. He currently has over 242 professional connections on LinkedIn.
More about this expert
- Full name
- Ian Roundtree
- Boston, Massachusetts, United States
- Resident Physician
- Massachusetts General Hospital (since 2020)
- Hospitals and Health Care
- LinkedIn profile
- LinkedIn Connections
- My interests in both research and medicine stem from training in synthetic organic chemistry and the application of chemical principles to biological systems. As an undergraduate researcher, my work focused on developing and applying methods towards synthesis of biologically active small molecules. As a graduate researcher, I worked to establish reversible mRNA methylation as a novel mode of genetic regulation, and elucidated the role for methylation in various biological processes. The establishment of RNA methylation as a novel regulatory node changed our view of RNA as an information carrying entity, and added an additional layer of complexity to our understanding of gene expression - RNA epigenetics. The ultimate goal of my career is to continue to challenge the fundamental beliefs about biology and disease in order to identify unique biological principles and exploit these findings as potential modes of therapy.
- Molecular Biology RNA Sequencing
- The University of Chicago Pritzker School of Medicine
Attended in 2012
- University of Chicago
Doctor of Philosophy - PhD
Attended in 2012 - 2017
Field of study: Biochemistry
Massachusetts General Hospital
Boston, Massachusetts, United States
Jun 2020 - Present
University of Chicago
Chicago, Illinois, United States
Jun 2012 - Jun 2020
Jan 2010 - Jul 2012 · 2 yrs 7 mos
Research Associate, Chemistry
Jan 2010 - Jul 2012
Developed synthetic methods in organic chemistry aimed at generating organoboron compounds for construction of carbon-carbon bonds from inexpensive starting materials, and their application in enantioselective cross-coupling reactions in total synthesis of complex natural products.
Jan 2010 - Jul 2012 · 2 yrs 7 mos
Sep 2009 - Jun 2012
Provided oversight to intramural leagues, including scheduling of activities and training of officials. Provided emergency medical care during intramural events.